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SIMTRUM Spotlight for May 2023 | SIMTRUM Photonics Store

Technological Innovations Announced: High-Precision Laser Confocal Microscope and High-Efficiency Laser Line Scanning Confocal Microscope Now Available - The SIMTRUM Spotlight for May 2023

2023-05-10

Dear SIMTRUM Insider,


We are excited to introduce two new blockbuster products, Laser Scanning Confocal Microscope - SIMSCOP P seriesLaser Line Scan Confocal Microscope - SIMSCOP L Series. This is the latest scientific and technological achievement of our R&D Center in Guangzhou. We are committed to bringing you the most advanced and efficient photonics solutions, enabling you to achieve breakthroughs in your field of research.  


The Laser scanning confocal microscope uses a laser light source to acquire images through single-point scanning, providing an ultra-clear microscopic observation experience with high resolution and high contrast. Since it receives light only at the focal point, background noise around the sample is hugely reduced. It can also generate a 3D image of the sample by scanning at different depth planes. This microscope provides real-time, sharp, high-contrast images regardless of the environment and lighting conditions. More importantly, it has minimal damage to samples and is suitable for precisely observing living or sensitive samples. And our Laser Scanning Confocal Microscope - SIMSCOP P series achieves an outstanding balance between function, cost and flexibility.


Key Advantage

● Professional software UI with great featuress for imaging analysis

● Single or Multi laser Channel, laser power control accuracy up to 0.01%

● Silicon PMT detector enabling higher photon dynamic range and less noise

● Support high-speed scanning: 30fpx@512x512Pixels (resonant scanner)

● Compact Modular design, able to adapt to most microscope system

● Multiple upgrade options for future capability expansion with low cost

Click Here for more info


The working principle of the laser line scanning confocal microscope is similar to that of the laser scanning confocal microscope, which uses laser light to scan and acquire images. But the difference is that laser line scanning confocal microscopes scan an entire line at once, not just a spot. This allows it to scan the entire sample faster, increasing the speed of image acquisition. 


Our Laser Line Scan Confocal Microscope - SIMSCOP L Series is a novel way to microscope observation that achieves deeper penetration depth based on a confocal microscope. Using the combination of the electro-optic modulator and self-designed liquid crystal phase plate, only the intensity of signal fluorescence at the focal point is modulated, while stray light and background light is not modulated. Through the principle of modulation and demodulation technology, a strong focal area signal is extracted, thereby improving the signal-to-noise ratio and signal-to-background ratio of the image by 20-30dB, improving the imaging depth. We have added a cylindrical lens that creates a line focus on the sample and enables line scan imaging, so the imaging acquisition speed is significantly increased compared to conventional point scanning confocal microscopes. 


Key Advantages

Superior Resolution: At its core is a focal modulation module for high-contrast imaging. It significantly reduces the background signal caused by multiple scattering and effectively picks up the high-resolution signal related to the ballistic excitation light. Consequently, the signal to background ratio and the spatial resolution can be maintained to a deeper penetration depth, which is about two to four times deeper than conventional confocal microscopes.

High Acquisition Speed: Capturing at speeds at least 100x faster than conventional confocal technology, LFMM is the optimal solution for live cell and tissue imaging, providing low phototoxicity and photobleaching, or perfect for fast volume acquisition of fixed samples and even small live animals.

Large Field of View: Our scientific CMOS camera can offer a sensor up to 5.5 Megapixel, yielding the largest available field of view with 60x objectives (0.36 mm) and 40x objectives (0.54 mm). Maximizing view in fluorescence microscopy is of increasing relevance across a wide range of applications, including high content screening of large fields of cells, imaging of the developing embryo, neuron mapping and tissue imaging.

Versatility: The Laser Line Scan Confocal Microscope is adaptable to a broad range of applications, making it an invaluable asset for any research facility.


Features & Benefits

√ High-speed acquisition

√ Strong optical sectioning

√ Single molecule imaging

√ Multi-color fluorescence

√ High sensitivity

√ Large field of view

√ Low photobleaching and phototoxicity

√ Super-resolution

√ Intuitive software

Click Here for more info


During the same period, SIMTRUM also launched Spinning Disk Confocal Microscope - SpinDisk Base & SpinDisk Advance, and Structured Illumination Microscope - SIM & SpinDisk SIM. These two series are in our Specialized Microscopy family as well. They are both advanced imaging tools used in scientific research, but they differ in their working principles, speed, resolution, and suitability for different types of samples. For more information please click on the images to reach the product pages.

Spinning Disk Confocal Microscope - BaseSpinning Disk Confocal Microscope - Advance


Structured Illumination Microscope - SIM
Structured Illumination Microscope - SpinDisk SIM


The best choice of a microscope depends on the specific requirements of your experiments and samples, including factors like speed, resolution, phototoxicity, depth of imaging, and three-dimensional reconstruction needs. All the products adopt the latest optical technology and high-quality materials, which are impeccable in terms of performance stability and durability, and bring new possibilities to the fields of life research, medical treatment, industry or material science. You can click Here for more information about the Specialized Microscope. If wanting to place an order, please click Contact Us to reach our sales team.

 

We appreciate your support and interest in our products. As we step into this new venture, we eagerly anticipate the remarkable discoveries that this tool will facilitate.


We have custom solutions available for Microscopy solutions | Spectroscopy solutions, to learn more about SIMTRUM's own products, click Here

Please feel free to Contact Us for any requirements or inquiries.


SIMTRUM Marketing